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Phenothiazine possible effect

Hi Jytdog, I receive your edit war warning. I would like to let you know that the Phenothiazine could possibly trigger antiphospholipid syndrome as described in the session "Other clinical associations" aPL(Antiphospholipid) antibodies are also found in association with phenothiazines, such as described in Antiphospholipid Syndrome Antiphospholipid Syndrome among in the original link i posted to the article Liwk (talk) 08:54, 26 July 2015 (UTC)[reply]

Thanks for talking. It is best to do this at the article talk page - if you would like to post there, i'll response there. thanks! Jytdog (talk) 08:58, 26 July 2015 (UTC)[reply]

Ok, i will move this to the talk page there then. Liwk (talk) 09:08, 26 July 2015 (UTC)[reply]

Thanks for talking! What that source says is that the cause is unknown. It lists several things that "are associated with" the condition. Side effects are actually caused by a drug. Jytdog (talk) 09:15, 26 July 2015 (UTC)[reply]

Thank you for your opinions. The first source from American Association for Clinical Chemistry states that "APS can also be seen in the elderly and temporarily during infections and with some medications, such as the psychiatric drugs phenothiazine" and the second source states that "Antiphospholipid Syndrome is associated with phenothiazine". So I think it is fair to state that antiphospholipid syndrome is a possible effect with phenothiazine.

The mechanism is stated in some sources, like Am J Clin Pathol that "These findings demonstrate the heterogeneity of antiphospholipid antibody specificity induced in patients treated with various phenothiazine drugs ...", and Translationsional Development Psychiatry"Among the existing antipsychotics, phenothiazines are causally associated with APS" Liwk (talk) 10:59, 26 July 2015 (UTC)[reply]

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 ::Ok, i will move this to the talk page there then. [[User:Liwk|Liwk]] ([[User talk:Liwk|talk]]) 09:08, 26 July 2015 (UTC)
 :::Thanks for talking!  What that source says is that the cause is unknown.  It lists several things that "are associated with" the condition.   Side effects are actually ''caused'' by a drug. [[User:Jytdog|Jytdog]] ([[User talk:Jytdog|talk]]) 09:15, 26 July 2015 (UTC)
+::::Thank you for your opinions. The first source from American Association for Clinical Chemistry  states that "APS can also be seen in the elderly and temporarily during infections and with some medications, such as the psychiatric drugs phenothiazine" and the second source states that "Antiphospholipid Syndrome is associated with phenothiazine". So I think it is fair to state that  antiphospholipid syndrome is a <i>possible effect</i> with phenothiazine.
+::::The mechanism is stated in some sources, like [http://www.ncbi.nlm.nih.gov/pubmed/1971739 Am J Clin Pathol] that "These findings demonstrate the heterogeneity of antiphospholipid antibody specificity induced in patients treated with various phenothiazine drugs ...", and [http://www.translationaldevelopmentalpsychiatry.net/index.php/tdp/article/view/25452 Translationsional Development Psychiatry]"Among the existing antipsychotics, phenothiazines are causally associated with APS" [[User:Liwk|Liwk]] ([[User talk:Liwk|talk]]) 10:59, 26 July 2015 (UTC)