1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase

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1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
4wd0.jpg
HisAp hexamer, Arthrobacter aurescens
Identifiers
EC number5.3.1.16
CAS number37318-43-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16, N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5-phosphoribosyl)-4-imidazolecarboxamide isomerase, phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase, N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase) is an enzyme with systematic name 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide aldose-ketose-isomerase.[1] This enzyme catalyses the following chemical reaction

1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide

References[edit]

  1. ^ Margolies MN, Goldberger RF (July 1966). "Isolation of the fourth (isomerase) of histidine biosynthesis from Salmonella typhimurium". The Journal of Biological Chemistry. 241 (14): 3262–9. PMID 5330429.

External links[edit]