16S rRNA (guanine966-N2)-methyltransferase
| 16S rRNA (guanine966-N2)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.171 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
16S rRNA (guanine966-N2)-methyltransferase (EC 2.1.1.171, yhhF (gene), rsmD (gene), m2G966 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine966-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine966 in 16S rRNA S-adenosyl-L-homocysteine + N2-methylguanine966 in 16S rRNA
The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro.
References
- ^ Lesnyak, D.V.; Osipiuk, J.; Skarina, T.; Sergiev, P.V.; Bogdanov, A.A.; Edwards, A.; Savchenko, A.; Joachimiak, A.; Dontsova, O.A. (2007). "Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure". J. Biol. Chem. 282: 5880–5887. doi:10.1074/jbc.m608214200. PMID 17189261.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
External links
- 16S+rRNA+(guanine966-N2)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)