The 1915 Oklahoma Sooners football team represented the University of Oklahoma in the 1915 college football season. In their 11th year under head coach Bennie Owen, the Sooners compiled a 10–0 record (3–0 against conference opponents), and outscored their opponents by a combined total of 370 to 54. This was the first season that the Sooners participated in the Southwest Conference. The team was retroactively selected as the national champion for 1914 by the Billingsley Report using its alternate "margin of victory" methodology.
One Sooner was recognized as an All-American: Forest Geyer.
Six Sooners received All-Southwest Conference honors: Elmer Capshaw, Forest Geyer, Oliver Hot, Willis Hott, Hap Johnson, and Homer Montgomery.