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3-deoxy-D-manno-octulosonate aldolase

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3-deoxy-D-manno-octulosonate aldolase
Identifiers
EC no.4.1.2.23
CAS no.9026-95-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
PRIAMprofile
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The enzyme 3-deoxy-D-manno-octulosonate aldolase (EC 4.1.2.23) catalyzes the chemical reaction

3-deoxy-D-manno-octulosonate pyruvate + D-arabinose

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxyoctonate aldolase, KDOaldolase, 3-deoxyoctulosonic aldolase, 2-keto-3-deoxyoctonic aldolase, 3-deoxy-D-manno-octulosonic aldolase, and 3-deoxy-D-manno-octulosonate D-arabinose-lyase.

References

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  • Ghalambor MA, Heath EC (1966). "The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. V. Purification and properties of 3-deoxy-D-manno-octulosonate aldolase". J. Biol. Chem. 241 (13): 3222–7. PMID 5912115.