In enzymology, a 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC 126.96.36.199) is an enzyme that catalyzes the chemical reaction
- 4-deoxy-L-threo-5-hexosulose uronate 3-deoxy-D-glycero-2,5-hexodiulosonate
Hence, this enzyme has one substrate, 4-deoxy-L-threo-5-hexosulose uronate, and one product, 3-deoxy-D-glycero-2,5-hexodiulosonate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase. This enzyme is also called 4-deoxy-L-threo-5-hexulose uronate isomerase. This enzyme participates in pentose and glucuronate interconversions.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1X8M, 1XRU, and 1YWK.