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5-dehydro-2-deoxyphosphogluconate aldolase

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5-dehydro-2-deoxyphosphogluconate aldolase
Identifiers
EC no.4.1.2.29
CAS no.62213-25-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
PRIAMprofile
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The enzyme 5-dehydro-2-deoxyphosphogluconate aldolase (EC 4.1.2.29) catalyzes the chemical reaction

5-dehydro-2-deoxy-D-gluconate 6-phosphate glycerone phosphate[1] + malonate semialdehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming). Other names in common use include phospho-5-keto-2-deoxygluconate aldolase, 5-dehydro-2-deoxy-D-gluconate-6-phosphate, and malonate-semialdehyde-lyase.

References

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  1. ^ Glycerone phosphate is often called dihydroxacetone phosphate.
  • Anderson WA, Magasanik B (1971). "The pathway of myo-inositol degradation in Aerobacter aerogenes Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates". J. Biol. Chem. 246 (18): 5662–75. PMID 4328832.