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6-Hydroxyflavone

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6-Hydroxyflavone
Ball-and-stick model of 6-hydroxyflavone
Names
IUPAC name
6-hydroxy-2-phenylchromen-4-one
Other names
6-Monohydroxyflavone; 6-Hydroxy-2-phenyl-4-benzopyrone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.027.005 Edit this at Wikidata
EC Number
  • 229-704-8
KEGG
  • InChI=1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H checkY
    Key: GPZYYYGYCRFPBU-UHFFFAOYSA-N checkY
  • InChI=1/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H
    Key: GPZYYYGYCRFPBU-UHFFFAOYAV
  • C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O
  • O=C\1c3c(O/C(=C/1)c2ccccc2)ccc(O)c3
Properties
C15H10O3
Molar mass 238.242 g·mol−1
Melting point 234 to 236 °C (453 to 457 °F; 507 to 509 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India).[1] 6-Hydroxyflavone may have a potential as a therapeutic drug capable for the treatment of anxiety-like disorders.[2]

References

  1. ^ Medicinal plants, Chemistry and properties by M Daniel.
  2. ^ "GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone". ScienceDirect. Retrieved 2011-06-12.

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