6-methylsalicylate decarboxylase

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6-methylsalicylate decarboxylase
Identifiers
EC number4.1.1.52
CAS number37289-50-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a 6-methylsalicylate decarboxylase (EC 4.1.1.52) is an enzyme that catalyzes the chemical reaction

6-methylsalicylate 3-cresol + CO2

Hence, this enzyme has one substrate, 6-methylsalicylate, and two products, 3-cresol and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 6-methylsalicylate carboxy-lyase (3-cresol-forming). Other names in common use include 6-methylsalicylic acid (2,6-cresotic acid) decarboxylase, 6-MSA decarboxylase, and 6-methylsalicylate carboxy-lyase.

References[edit]

  • Light RJ (1969). "6-methylsalicylic acid decarboxylase from Penicillium patulum". Biochim. Biophys. Acta. 191 (2): 430–8. doi:10.1016/0005-2744(69)90262-9. PMID 5354271.
  • Vogel G; Lynen F (1970). "6-Methylsalicylsaure-Decarboxylase". Naturwissenschaften. 57: 664. doi:10.1007/BF00598791.