10-hydroxydihydrosanguinarine 10-O-methyltransferase
| 10-hydroxydihydrosanguinarine 10-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.119 | ||||||||
| CAS no. | 144388-39-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 10-hydroxydihydrosanguinarine 10-O-methyltransferase (EC 2.1.1.119) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine S-adenosyl-L-homocysteine + dihydrochelirubine
Thus, the two substrates of this enzyme are S-adenosyl methionine and 10-hydroxydihydrosanguinarine, whereas its two products are S-adenosylhomocysteine and dihydrochelirubine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
[edit]- De-Eknamkul W, Tanahashi T, Zenk MH (1992). "Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia". Phytochemistry. 31 (8): 2713–2717. doi:10.1016/0031-9422(92)83617-8.
