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Dimethylglycine N-methyltransferase

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Dimethylglycine N-methyltransferase
Identifiers
EC no.2.1.1.161
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Dimethylglycine N-methyltransferase (EC 2.1.1.161, BsmB, DMT) is an enzyme with systematic name S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming).[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + N,N-dimethylglycine S-adenosyl-L-homocysteine + betaine

This enzyme is purified from the marine cyanobacterium Synechococcus sp. WH8102.

References

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  1. ^ Lu WD, Chi ZM, Su CD (December 2006). "Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis". Archives of Microbiology. 186 (6): 495–506. doi:10.1007/s00203-006-0167-8. PMID 17019606. S2CID 25210214.
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