Phenol O-methyltransferase
| phenol O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.25 | ||||||||
| CAS no. | 37256-94-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a phenol O-methyltransferase (EC 2.1.1.25) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + phenol S-adenosyl-L-homocysteine + anisole
Thus, the two substrates of this enzyme are S-adenosyl methionine and phenol, whereas its two products are S-adenosylhomocysteine and anisole.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:phenol O-methyltransferase. This enzyme is also called PMT. This enzyme participates in tyrosine metabolism.
References
- Axelrod J, Daly J (1968). "Phenol-O-methyltransferase". Biochim. Biophys. Acta. 159 (3): 472–8. doi:10.1016/0005-2744(68)90131-9. PMID 5657870.
