Guanidinopropionase
Appearance
guanidinopropionase | |||||||||
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Identifiers | |||||||||
EC no. | 3.5.3.17 | ||||||||
CAS no. | 68821-77-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a guanidinopropionase (EC 3.5.3.17) is an enzyme that catalyzes the chemical reaction
- 3-guanidinopropanoate + H2O beta-alanine + urea
Thus, the two substrates of this enzyme are 3-guanidinopropanoate and H2O, whereas its two products are beta-alanine and urea.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is 3-guanidinopropanoate amidinopropionase. Other names in common use include GPase, and GPH. It employs one cofactor, manganese.
References
- Yorifuji T, Sugai I, Matsumoto H, Tabuchi A (1982). "Characterization of 3-guanidinopropionate amidinohydrolase from Pseudomonas aeruginosa and a comparative study with 4- guanidinobutyrate amidinohydrolase from another Pseudomonas". Agric. Biol. Chem. 46 (5): 1361–1363. doi:10.1271/bbb1961.46.1361.