Aspartylglucosaminidase

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AGA
Protein AGA PDB 1apy.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AGA, Aga, AW060726, AGU, ASRG, GA, aspartylglucosaminidase
External IDs MGI: 104873 HomoloGene: 13 GeneCards: 175
RNA expression pattern
PBB GE AGA 204332 s at tn.png

PBB GE AGA 204333 s at tn.png

PBB GE AGA 216064 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000027
NM_001171988

NM_001005847
NM_001205054

RefSeq (protein)

NP_000018.2
NP_001165459.1

NP_001005847.1

Location (UCSC) Chr 4: 177.43 – 177.44 Mb Chr 8: 53.51 – 53.52 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase is an enzyme that in humans is encoded by the AGA gene.[1]

Aspartylglucosaminidase is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme.[1]

References[edit]

Further reading[edit]

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