Ferredoxin:protochlorophyllide reductase (ATP-dependent)
| Ferredoxin:protochlorophyllide reductase (ATP-dependent) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.7.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Ferredoxin:protochlorophyllide reductase (ATP-dependent) (EC 1.3.7.7), light-independent protochlorophyllide reductase) is an enzyme with systematic name ATP-dependent ferredoxin:protochlorophyllide-a 7,8-oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction
- protochlorophyllide + reduced ferredoxin + 2 ATP + 2 H2O chlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
- Structure of the substrate and product of the enzyme
-
Protochlorophyllide -
Chlorophyllide a
It can alternatively take as its substrate the compound with a second vinyl group (instead of an ethyl group) in the structure, in which case the reaction is
- 3,8-divinylprotochlorophyllide + reduced ferredoxin + 2 ATP + 2 H2O 3,8-divinylchlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
This enzyme is present in photosynthetic bacteria, cyanobacteria, green algae and gymnosperms and is part of the biosynthetic pathway to chlorophylls.[4][5]
See also
References
- ^ Fujita Y, Matsumoto H, Takahashi Y, Matsubara H (March 1993). "Identification of a nifDK-like gene (ORF467) involved in the biosynthesis of chlorophyll in the cyanobacterium Plectonema boryanum". Plant & Cell Physiology. 34 (2): 305–14. PMID 8199775.
- ^ Nomata J, Ogawa T, Kitashima M, Inoue K, Fujita Y (April 2008). "NB-protein (BchN-BchB) of dark-operative protochlorophyllide reductase is the catalytic component containing oxygen-tolerant Fe-S clusters". FEBS Letters. 582 (9): 1346–50. doi:10.1016/j.febslet.2008.03.018. PMID 18358835.
- ^ Muraki N, Nomata J, Ebata K, Mizoguchi T, Shiba T, Tamiaki H, et al. (May 2010). "X-ray crystal structure of the light-independent protochlorophyllide reductase". Nature. 465 (7294): 110–4. doi:10.1038/nature08950. PMID 20400946.
- ^ Willows RD (June 2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (3): 327–41. doi:10.1039/B110549N. PMID 12828371.
- ^ Bollivar DW (November 2006). "Recent advances in chlorophyll biosynthesis". Photosynthesis Research. 90 (2): 173–94. doi:10.1007/s11120-006-9076-6. PMID 17370354.
External links
- Ferredoxin:protochlorophyllide+reductase+(ATP-dependent) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
