APOBEC3C

APOBEC3C
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3VM8, 3VOW
Identifiers
Aliases	APOBEC3C, A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3, apolipoprotein B mRNA editing enzyme catalytic subunit 3C
External IDs	OMIM: 607750; HomoloGene: 129856; GeneCards: APOBEC3C; OMA:APOBEC3C - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	39,020,352 bp
RNA expression pattern
	Top expressed in
	white blood cell; ; granulocyte; ; monocyte; ; lymph node; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; rectum; ; stromal cell of endometrium; ; smooth muscle tissue;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; catalytic activity; zinc ion binding; hydrolase activity; metal ion binding; RNA binding; cytidine deaminase activity;
Cellular component	nucleus; cytoplasm; P-body;
Biological process	negative regulation of viral genome replication; immune system process; defense response to virus; cytidine deamination; innate immune response; viral process; negative regulation of transposition; DNA demethylation; cytidine to uridine editing; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; DNA cytosine deamination;
	Sources:Amigo / QuickGO
Orthologs
	27350
	n/a
	ENSG00000244509
	n/a
	Q9NRW3
	n/a
	NM_014508
	n/a
	NP_055323
	n/a
	Wikidata
View/Edit Human

Probable DNA dC->dU-editing enzyme APOBEC-3C is a protein that in humans is encoded by the APOBEC3C gene.^[3]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000244509 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, Navaratnam N (Feb 2002). "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22". Genomics. 79 (3): 285–96. doi:10.1006/geno.2002.6718. PMID 11863358.
^ "Entrez Gene: APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C".

v t e Hydrolases: carbon-nitrogen non-peptide (EC 3.5)
3.5.1: Linear amides / Amidohydrolases	Asparaginase Glutaminase Urease Biotinidase Aminoacylase ACY1 Aspartoacylase(ACY2) ACY3 Ceramidase Aspartylglucosaminidase Fatty acid amide hydrolase Histone deacetylase Sirtuin
3.5.2: Cyclic amides/ Amidohydrolases	Barbiturase Beta-lactamase Dihydroorotase
3.5.3: Linear amidines/ Ureohydrolases	Arginase Agmatinase Protein-arginine deiminase
3.5.4: Cyclic amidines/ Aminohydrolases	Guanine deaminase Adenosine deaminase AMP deaminase Inosine monophosphate synthase DCMP deaminase GTP cyclohydrolase I Cytidine deaminase AICDA Activation-induced cytidine deaminase
3.5.5: Nitriles/ Aminohydrolases	Nitrilase
3.5.99: Other	Riboflavinase Thiaminase II

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)