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ARL4D

From Wikipedia, the free encyclopedia

ARL4D
Identifiers
AliasesARL4D, ARF4L, ARL6, ADP ribosylation factor like GTPase 4D
External IDsOMIM: 600732; MGI: 1933155; HomoloGene: 1255; GeneCards: ARL4D; OMA:ARL4D - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001661

NM_025404

RefSeq (protein)

NP_001652

NP_079680

Location (UCSC)Chr 17: 43.4 – 43.4 MbChr 11: 101.56 – 101.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ADP-ribosylation factor-like protein 4D is a protein that in humans is encoded by the ARL4D gene.[5][6]

Function

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ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet–Biedl syndrome (BBS).[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175906Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034936Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Smith SA, Holik PR, Stevens J, Melis R, White R, Albertsen H (Jul 1995). "Isolation and mapping of a gene encoding a novel human ADP-ribosylation factor on chromosome 17q12-q21". Genomics. 28 (1): 113–5. doi:10.1006/geno.1995.1115. PMID 7590735.
  6. ^ a b "Entrez Gene: ARL4D ADP-ribosylation factor-like 4D".
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Further reading

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