ATP5H

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ATP5H
Identifiers
Aliases ATP5H, ATPQ, ATP synthase, H+ transporting, mitochondrial Fo complex subunit D
External IDs MGI: 1918929 HomoloGene: 130552 GeneCards: ATP5H
RNA expression pattern
PBB GE ATP5H 210149 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006356
NM_001003785

NM_027862

RefSeq (protein)

NP_001003785
NP_006347

NP_082138.1
NP_082138

Location (UCSC) Chr 17: 75.04 – 75.05 Mb Chr 11: 115.42 – 115.42 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse
ATP synthase D chain, mitochondrial
Identifiers
Symbol ATP5H
Pfam PF05873

The human gene ATP5H encodes subunit d of the enzyme mitochondrial ATP synthase.[3][4]

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The F0 seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the F0 complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934Freely accessible. PMID 11042152. 
  4. ^ a b "Entrez Gene: ATP5H ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d". 

External links[edit]

Further reading[edit]