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The Alfred E. Mann Institute for Biomedical Engineering, commonly known as the Alfred Mann Institute, AMI or Mann Institute of Biomedical Engineering, is located on the University Park campus of the University of Southern California (USC). A business incubator for medical device development in preparation for commercialization, AMI was founded in 1998 when billionaire medical device entrepreneur and philanthropist Alfred E. Mann made a $100 million gift to USC, a major private research university in Los Angeles. The total gifted endowment for AMI, after similar donations from MannKind and the Alfred Mann Foundation totaled $160 Million.