All-trans-octaprenyl-diphosphate synthase
Appearance
All-trans-octaprenyl-diphosphate synthase | |||||||||
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Identifiers | |||||||||
EC no. | 2.5.1.90 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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All-trans-octaprenyl-diphosphate synthase (EC 2.5.1.90, octaprenyl-diphosphate synthase, octaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-heptaprenyltranstransferase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate 5 diphosphate + all-trans-octaprenyl diphosphate
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate.
References
[edit]- ^ Fujisaki S, Nishino T, Katsuki H (May 1986). "Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis". Journal of Biochemistry. 99 (5): 1327–37. doi:10.1093/oxfordjournals.jbchem.a135600. PMID 3519603.
- ^ Asai K, Fujisaki S, Nishimura Y, Nishino T, Okada K, Nakagawa T, Kawamukai M, Matsuda H (July 1994). "The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase". Biochemical and Biophysical Research Communications. 202 (1): 340–5. doi:10.1006/bbrc.1994.1933. PMID 8037730.
External links
[edit]- All-trans-octaprenyl-diphosphate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)