Amylocaine

Amylocaine
Names
	IUPAC name benzoic acid [1-(dimethylaminomethyl)-1-methylpropyl] ester
Identifiers
CAS Number	644-26-8 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1740065 ;
ChemSpider	10312 ;
ECHA InfoCard	100.010.375
KEGG	D07454 ;
PubChem CID	10767;
UNII	QRW683O56T ;
CompTox Dashboard (EPA)	DTXSID6047862 ;
	InChI InChI=1S/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3 Key: FDMBBCOBEAVDAO-UHFFFAOYSA-N ; InChI=1/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3 Key: FDMBBCOBEAVDAO-UHFFFAOYAQ;
	SMILES O=C(OC(C)(CC)CN(C)C)c1ccccc1;
Properties
Chemical formula	C14H21NO2
Molar mass	235.32204
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Amylocaine was the first synthetic local anesthetic. It was synthesized and patented under the name Stovaine by Ernest Fourneau at the Pasteur Institute in 1903.^[1] It used to be used mostly in spinal anesthesia.^[2]

Notes and references

^ Fourneau, E. (1904). "Stovaïne, anesthésique local". Bulletin des sciences pharmacologiques. 10: 141-148.
^ Debue-Barazer, Christine (2007). "Les Implications scientifiques et industrielles du succès de la Stovaïne : Ernest Fourneau (1872-1949) et la chimie des médicaments en France". Gesnerus 64 (1-2): 24-53.

Smith, Maurice I.; Hatcher, Robert A. (January 1917). "A Contribution to the Pharmacology of Stovaine". Journal of Pharmacology and Experimental Therapeutics. 9 (4): 231–240.
Ball, Christine M.; Westhorpe, Rod N. (2004). "Local Anaesthesia after Cocaine". Anaesthesia and Intensive Care. 32 (2): 157. PMID 15957711.

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