Benzoin aldolase

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benzoin aldolase
Identifiers
EC number 4.1.2.38
CAS number 122097-01-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a benzoin aldolase (EC 4.1.2.38) is an enzyme that catalyzes the chemical reaction

2-hydroxy-1,2-diphenylethanone 2 benzaldehyde

Hence, this enzyme has one substrate, 2-hydroxy-1,2-diphenylethanone, and one product, benzaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming). Other names in common use include benzaldehyde lyase, and 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase. It employs one cofactor, thiamin diphosphate.

Structural studies[edit]

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2AG0, 2AG1, and 2UZ1.

References[edit]