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Deoxyuridine

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Deoxyuridine
Skeletal formula of deoxyuridine
Ball-and-stick model of the deoxyuridine molecule
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.012.232 Edit this at Wikidata
MeSH Deoxyuridine
UNII
  • InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1 checkY
    Key: MXHRCPNRJAMMIM-SHYZEUOFSA-N checkY
  • InChI=1/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
    Key: MXHRCPNRJAMMIM-SHYZEUOFBK
  • O=C/1NC(=O)N(\C=C\1)[C@@H]2O[C@@H]([C@@H](O)C2)CO
Properties
C9H12N2O5
Molar mass 228.202
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Deoxyuridine (dU) is a compound and a nucleoside. It is similar in chemical structure to uridine, but without the 2'-hydroxyl group.

Idoxuridine and Trifluridine are variants of deoxyuridine used as antiviral drugs. They are similar enough to be incorporated as part of DNA replication, but they possess side groups on the uracil component (an iodine and a CF3 group, respectively), that prevent base pairing.

A known use of dU is as a precursor in the synthesis of Edoxudine.