Djibouti and Kenya first established diplomatic ties on 27 June 1977, after Djibouti's independence.
In 2011, while on tour of Djibouti, Kenya's Ambassador Extra-Ordinary and Plenipotentiary, Monica K. Juma met with Djiboutian President, Ismail Omar Guelleh. She also held talks with the Djiboutian Minister for Foreign Affairs, Speaker of the National Assembly, Minister for Education, Minister for Transport, the Chamber of Commerce, the investment promotion agency and the tourism board.
In 2005, Djibouti exported $1.4 million USD worth of commodities to Kenya. Around 11% or $8.7 million USD of Djibouti's total imports also consisted of goods from Kenya. In addition, Djibouti has bilateral trade and cooperation agreements with Kenya.