Enkurin

ENKUR
Identifiers
Aliases	ENKUR, C10orf63, CFAP106, enkurin, TRPC channel interacting protein
External IDs	OMIM: 611025; MGI: 1918483; HomoloGene: 17022; GeneCards: ENKUR; OMA:ENKUR - orthologs
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	21,210,176 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; right uterine tube; ; monocyte; ; bone marrow cells; ; hypothalamus; ; caudate nucleus; ; ganglionic eminence; ; putamen; ; nucleus accumbens; ; amygdala;
	Top expressed in
	seminiferous tubule; ; olfactory epithelium; ; otolith organ; ; utricle; ; spermatid; ; vestibular sensory epithelium; ; spermatocyte; ; right lung lobe; ; median eminence; ; Epithelium of choroid plexus;
	More reference expression data
	n/a
Orthologs
	219670
	71233
	n/a
	ENSMUSG00000026679
	Q8TC29
	Q6SP97
	NM_001270383; NM_145010
	NM_027728
	NP_001257312; NP_659447
	NP_082004
	Wikidata
View/Edit Human	View/Edit Mouse

Enkurin is a protein that in humans is encoded by the ENKUR gene.^[4]^[5]

Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (e.g., TRPC1) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels.^[5]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026679 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: enkurin".
^ ^a ^b Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM (October 2004). "Enkurin is a novel calmodulin and TRPC channel binding protein in sperm". Dev. Biol. 274 (2): 426–35. doi:10.1016/j.ydbio.2004.07.031. PMID 15385169.

Beech DJ (2007). "Canonical transient receptor potential". Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology. Vol. 179. pp. 109–23. doi:10.1007/978-3-540-34891-7_6. ISBN 978-3-540-34889-4. PMID 17217053.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000026679 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: enkurin".

[pmid15385169-5] Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM (October 2004). "Enkurin is a novel calmodulin and TRPC channel binding protein in sperm". Dev. Biol. 274 (2): 426–35. doi:10.1016/j.ydbio.2004.07.031. PMID 15385169.

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References

Further reading