GSK China scandal

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The GSK China scandal unfolded when the China division of the global drugmaker GlaxoSmithKline (GSK) admitted to engaging in bribery to promote its products within the Chinese market. The scandal originated with the discovery of sex tapes featuring Mark Reilly, the head of GSK's operations in China, and his Chinese girlfriend, circulated among senior company executives. This revelation prompted internal investigations by GSK, which in turn led to the imprisonment of investigator Peter Humphrey and his wife, Yu Yingzeng, in China. The opaque judicial system in China, notorious for its high conviction rate, saw the couple facing charges of violating privacy laws. Humphrey and his wife assert their innocence, with Humphrey alleging torture and denial of medical treatment as a consequence of his refusal to confess to what he deems fabricated accusations.

In September 2014, following a trial in Changsha, GSK issued a public apology to the Chinese populace and agreed to pay one of the largest fines in Chinese history, totaling ¥3 billion (£300 million; €350 million; $490 million). Four company executives, including Mark Reilly, the sole foreign nationals implicated, received sentences. Reilly received a suspended sentence and was subsequently deported from China. The UK Serious Fraud Office wrapped up its investigation in 2019 after determining insufficient evidence to pursue further legal action.[1]

Background[edit]

Loose control over foreign companies[edit]

Since 1978, China embarked on a path of economic reform, transitioning towards a more market-oriented economy and opening its doors to global corporations.[2][3] As noted by American legal academic Jerome Cohen, there had been a longstanding policy of leniency towards foreign enterprises, aimed at avoiding embarrassment and dispelling the notion of widespread corruption within China. However, this mindset has shifted in recent years.[3]

China's evolving economic nationalism, which prioritizes domestic companies over foreign counterparts, has resulted in heightened scrutiny of foreign firms operating within its borders. This shift in approach underscores a departure from previous practices, as the Chinese government increasingly emphasizes the promotion and protection of its own industries.

Corruption in China's healthcare system[edit]

According to experts, China's healthcare system has been plagued by corruption, with reports of counterfeit vaccines and instances of doctors accepting bribes to bolster their financial standing. Leon Liu, a partner at the Shanghai-based law firm MWE China, highlights that corruption has contributed to inflated drug prices, adversely affecting Chinese citizens. Recognizing the need for reform, the Chinese government aimed to address these issues.Despite prior investigations into Chinese companies by the government and growing concerns about corruption in the healthcare sector,[4] GSK seemingly overlooked the shifting dynamics of the Chinese market. The company failed to heed warnings regarding bribery practices in China, ultimately leading to the scandal.[5]

Whistleblower of the China scandal[edit]

Emails to Chinese regulators[edit]

Between December 2011 and April 2012, a series of 24 anonymous tips originating from within GSK China were sent to Chinese regulators, detailing instances of fraud and corruption within the company. These reports, unbeknownst to high-ranking GSK executives until April 2012, revealed illicit practices within the company's operations in China, including improper marketing techniques and kickbacks to healthcare professionals. Despite assurances made to US regulators in July 2012 regarding the cessation of improper marketing practices and kickbacks, GSK continued these activities within China.[6]

In the midst of these revelations, Vivian Shi (Chinese: 施文; pinyin: Shī Wén), GSK's head of government affairs in China, found herself dismissed from her position, ostensibly due to allegations of falsifying travel expenses.[5][7] However, suspicions arose that Shi may have been the whistleblower behind the anonymous tips. Utilizing her connections within the Chinese political system, Vivian Shi allegedly played a role in the arrest of Peter Humphrey on what he claims were fabricated charges, further entangling the scandal within the complexities of China's legal and political landscape.

Emails to GSK headquarter[edit]

In January 2013, the board of GlaxoSmithKline (GSK) received a detailed email, spanning 5,200 words and written in English, alleging fraudulent activities within its China operations. The email outlined various accusations, including the practice of disguising tourist travel as international academic meetings, during which GSK China allegedly funded airline tickets and hotel accommodations for Chinese medical professionals in exchange for favorable promotion of the company's products. Furthermore, the email accused GSK China of falsifying its financial records to facilitate the illegal marketing of drugs in China. One specific example provided in the email involved the drug Lamictal, which had been approved in China solely for the treatment of epilepsy. However, GSK China purportedly aggressively marketed the drug for bipolar disorder, a use for which it was not approved. Tragically, this misrepresentation reportedly resulted in the death of a patient. Rather than address the issue transparently, GSK allegedly chose to pay approximately $9,000 to silence the patient. These allegations, if substantiated, paint a troubling picture of unethical behavior within GSK's China operations, highlighting potential breaches of both medical regulations and ethical standards.[5]

Bribery to Chinese regulators[edit]

However, despite the seriousness of the allegations, the whistleblower's warnings were dismissed as nothing more than a "smear campaign," according to a confidential report obtained by the New York Times. Additionally, Xinhua, a state-run media agency, reported that regulators across China had been receiving tips about GSK's bribery practices for years prior to the scandal. In an apparent attempt to address these concerns, in 2012, Mike Reilly, Zhang Guowei (Chinese: 张国维), and Zhao Hongyan (Chinese: 赵虹燕), executives at the company, purportedly established a risk management unit to handle such tips. Allegations emerged that GSK executives had engaged in bribery to influence regulators, prompting them to shift their focus from "commercial bribery" to "unequal competition." The executives acknowledged efforts to limit fines to a mere $50,000, but these attempts proved unsuccessful. This revelation underscores the extent to which GSK was allegedly willing to go to mitigate the consequences of its actions.[3]

Sex tape of the China head[edit]

In March, 13 executives of the company's London headquarter, including the CEO Andrew Witty, received an email with a sex tape as an attachment from an anonymous writer called "gskwhistleblower."[8] The secretly filmed tape showed Mark Reilly's sex with his girlfriend. The film had been edited to disguise the location, but had been filmed in the bedroom of Mr.Relly's Shanghai apartment. After receiving the email he moved to a more secure location.[9][8] The email accused the company and Mark Reilly of using China Comfort Travel to bribe doctors.

GSK investigation into the whistleblower[edit]

In April 2013, Mark Reilly, GSK's China head paid Peter Humphrey's ChinaWhys, a small risk consultancy which served Dell and Dow Chemical, to investigate into the break-in at his apartment and estimate the potential influence of the fired former employee, Vivian Shi, who was thought to be the whistleblower, in the government. Humphrey believed he was investigating a smear campaign. He visited Lanson Place where the tape was filmed and compiled a dossier of the potential suspects. On 6 June 2013, Humphrey submitted a report to GSK where he believed Shi to be the responsible party.[5]

Internal investigation[edit]

GSK's China business was plagued with alleged bribery. 56 employees in China were dismissed in the year before the scandal, among a total of 312 dismissals. Although the company did investigate into the allegations stated by the whistleblower, a week before the Chinese investigation, the internal investigation was concluded with "no evidence of corruption or bribery in our China business." The New York Times said an internal audit in 2011 already show serious problems in GSK China's facility.[10]

Police investigations[edit]

Early evidence[edit]

The Chinese police denied that it was because of the internal conflicts and tips from inside the company that they launched the investigation.[11]

According to Xinhua,[12] a state run media outlet, and the police report,[11] the Chinese investigations started with an investigation into an unknown Shanghai travel agency in early 2013.[11] According to Shanghai-based media the Economic Observer, the travel agency, namely Shanghai Linjiang International Travel Agency Co., Ltd. (Chinese: 上海临江国际旅行社有限公司), was founded 7 years ago before the investigation, by a Shanghai real estate developer and a major Chinese footballer.[13] The Chinese police said that the travel agency had few products but its revenue rose from million to hundreds of millions RMB. An investigation into the travel agency with help from other government offices identified its links to GSK and other pharmaceutical companies.[11]

Police action[edit]

The Public Security Ministry assigned Changsha Police to form a task force to investigate into the lead. The task force gathered evidence for GSK's bribery in ten plus Chinese provinces including Beijing, Shanghai, Liaoning, Xinjiang in a year-long period.[12] Shanghai and Zhengzhou Police were also assigned to make the investigation into the suspected economic crimes.[11]

On 27 June and 10 July 2013, the Changsha Police, with the help from Shanghai and Zhengzhou Police, carried out raids in multiple GSK offices and related travel agencies in Beijing, Shanghai, and Nanjing, acquiring files and laptops and interrogating employees.[11] 4 executives were arrested in Shanghai, including Mike Reilly, the company's China head and protagonist of the sex tape.[14] A total of 14 were arrested.[11] The Changsha Police announced the operation in a short statement on Weibo on 28 June.[11] Besides, AstraZeneca,[15][16] UCB[16] and other pharmaceutical companies' employees were also questioned by the State Administration for Industry and Commerce and the police.

GSK response[edit]

Mike Reilly left China on 27 June when police took action at GSK China, which was not stopped by the police. In a police press, head of China's fraud unit Gao Feng said GSK was the boss in the bribery networks. Gao continued, "This is a very serious violation and a high-profile case. We are wondering why we have not received any information. As for the chief of the China business, you had better ask him yourself why he has left China and is not willing to return so far." But he also said he was willing to cooperate with overseas partners. GSK responded that it would closely cooperate with the Chinese authorities.[17] Later, Reilly voluntarily returned to China to help the police with the investigations.[4]

Chinese media coverage[edit]

Bribery to doctors[edit]

The patent of GSK's leading hepatitis drug, Heptodin, expired in 2006. To cope with this, the company launched Changcheng (Chinese: 长城计划; lit. 'Great Wall Project') and Longteng (Chinese: 龙腾计划; lit. 'Dragon Flying Project') where the company used bribery to avoid Chinese doctors using Chinese equivalent of Heptodin.[18][19]

According to Gao Feng, head of the economic crimes investigation unit at China's Public Security Ministry, GSK transferred 3 billion yuan to over 700 travel agencies and consultancies during a 6-year period, through which the company bribed doctors, hospitals, officials and medical associations.[20] GSK bought services from the travel agencies at prices much higher than real prices, so that the agencies were able to serve as a fund for bribery which was independent of internal financial regulations of the company.[21]

Xinhua described the hierarchy of GSK's bribery networks, where the company reps bribed ordinary doctors, area managers bribed major clients, regional manager bribed VIPs, the marketing department bribed academics, and the VIP department bribed institutes. To avoid regulation, the company paid 7 smaller drug companies including Jiangsu Tailing (Chinese: 江苏泰陵医药) to sell its products. The company bought cars, cameras, televisions, electrical autos and other non-medical equipment to bribed centers of disease control and vaccine injection centers for ¥13m.[19]

Distorted drug prices[edit]

GSK's Lamivudine was priced at 142 RMB in mainland China, while it only cost 18RMB, 26RMB, 30RMB to buy the drug in Korea, Canada and Britain respectively. Adefovir Dipivoxil, another product of GSK, was as expensive as 182 RMB, but it only costs 103.5RMB and 59.92RMB to buy them in Japan and Hong Kong. The police investigation also showed how GSK manipulated their drug prices in China, which took 5 measures:[22]

  1. The company would first do market research in China. If there were similar drugs in China, they would make the prices of the drugs as a reference, or else, the company could price the drug "as high as it wanted."
  2. GSK China then reported the prices to the financial sector of GSK.
  3. GSK then sent the prices in China to GSK's transfer pricing (TP) center to calculate the importing prices and cost prices.
  4. When the prices were approved by the TP center, GSK China would import the drugs at the calculated importing prices.
  5. GSK China then would apply for approval from China's Development and Reform Commission for a new price based on the calculated importing price.

Chen Hongbo (Chinese: 陈洪波), former manager of GSK China, said to Xinhua that transfer pricing was a common strategy of multinationals, where a product was first sold to a middle country at a high price, and then it was imported to the destination at an even higher price based on the sale price in the middle country. Another way was to import raw materials for drugs. For example, Zinacef's raw material was packed in Cyprus and then was imported to Italy at a transferred price. After bottled in Italy, the bottled drug was imported to China at a much higher price. After it was labelled in China, the price would be even higher. The police told media that during 2009–12, GSK China's revenues of main business were ¥397.8m, ¥486.2m, ¥552.9m, ¥697.5m, but profits were merely ¥11m, ¥-4.7m, ¥6.0m, ¥-18.8m, which was owing to the company's transfer pricing strategy. Another manager of the company Liang Hong (Chinese: 梁宏) said that this helped the company avoid taxation in China.[22]

GSK used bribery to stimulate the sales of extravagantly expensive drugs. A GSK rep told Xinhua that her boss said to her, "if the doctor wants money, then give them money; if the doctor wants academic achievements, then provides them with the opportunity." Liang Hong estimated that 30% of the drug prices were used in bribery in GSK China's sales. Although the compliance department and Internal Audit Department of GSK China showed evidence to the company that the company was faking invoices and fabricating records and books, the warnings were not taken seriously. Lan Shengke (Chinese: 兰省科), an executive of GSK China, said that Mike Reilly even fired a director at the compliance department as the strict enforcement of the compliance rules affected sales performance in 2011.[22]

Court ruling[edit]

The trial on the company's commercial bribery was held in the Chinese city of Changsha on 19 September 2014.[23] According to Xinhua, the trial at Changsha Intermediate People’s Court was not public as requested by GSK who wanted to keep business secrets. Mike Reilly was sentenced to 3-year jail sentences with 4-year suspension and deportation from China. Other three Chinese GSK employees were sentenced to 2 to 4 years.[12] The company was sentenced to a record 3 billion yuan fine.[24]

The fine was the largest corporate fine in China, but GSK did not defend its actions. In a statement after the trial, the company said it "apologizes to the Chinese patients, doctors and hospitals, and to the Chinese government and the Chinese people." The company said it had learnt from the mistakes and would do "tangible actions to establish itself as a model for reform in China’s healthcare industry." The company also promised to continue to invest in China and would change its incentive program fundamentally.[25] A source told China Business Networks that the sales group for hepatitis drugs, which was related to the company's bribery plans, was downsized after the scandal.[18]

Impact[edit]

Sales strategies of GSK[edit]

Although the China market only contributed to a small fraction of overall revenue of GSK, it is the fastest-growing markets of the company. The company had heavily invested in the market, where it built both clinical and research facilities.[26] GSK's sales in China recorded a 25% drop in the second quarter of 2014. Globally, the quarterly profits fell by 14% to £1.3bn, which was below analysts' forecasts, leading to a 5% fall in its shares price, the biggest single fall on FTSE 100. The company still faced investigation by UK's Serious Fraud Office and US department of justice, due to the laws against overseas corruption in the two countries where GSK was listed.[26][27]

The legal suits in China forced the company to make a statement in December 2013, where changes in incentive programs, including cancelling individual sales targets and related bonus, were put forwards and expected to be enforced since 2014. To educate doctors about its products "transparently and without any perception of conflict of interest," the company also aimed to stop direct payment to any attendees at medical conferences by 2016, which was considered a significant move by the British Medical Association.[28]

Following the scandal, GSK promised to lower the prices of its products in China, which was regarded as a signal to other drugmakers in China.[21][29] National Development and Reform Commission said it would examine the drug prices by 60 firms,[29] after it had succeeded in making some foreign infant formula producers to lower the price in an earlier price-related inquiry.[30] But the low prices was predicted not to last long without a systematic change to China's healthcare system.[21] Many Chinese doctors said they had no choice but to use these foreign drugs, when Chinese patients had little trust in the quality of the Chinese equivalents.[31]

Foreign firms in China's anti-corruption campaign[edit]

For a long time, corruption had been usually considered as part of the cost of doing business in China, and the medical industry was no exception.[32] GSK's case occurred during the backdrop of Xi Jinping's anti-corruption campaign, which was believed to be focused on eliminating political opponents rather than stamping out corruption.[33] Ben Cavender, an associate principal at China Market Research Group, said that the GSK's case could be part of the greater trend of fighting against corruption, where foreign firms were advised to carefully obey the law.[32] However, the American Chamber of Commerce in China and US-China Business Council published reports, saying that foreign companies in China felt increasingly targeted by Chinese regulators. The president of the US-China Business Council doubted whether China was using such kinds of probes to protect its domestic industry.[25]

The anti-corruption effort backfired at the communication between international pharmaceutical firms and Chinese academics and local firms. A senior research director in Shanghai admitted money-involving new cooperation between international pharmaceutical firms and Chinese academics and hospitals were suspended in 2013.[21] Pharmaceutical companies usually invested in continuing medical education (CME) where the latest medical progress was discussed in order to encourage doctors to use their products. While CME was strictly regulated in Europe and the US, there was little oversight in emerging markets such as China.[34] In China, foreign pharmas were usually the ones who paid for the educational programs that few Chinese companies paid.

Aftermath[edit]

Humphrey's privacy breach[edit]

According to lawyers via the Financial Times, China's privacy law had become from one of the loosest one to a tighter one. In 2009, the country amended the criminal law to prohibit illegal transfer or trade of personal data and punish anyone who wants to buy or sell them. Violation of the law can lead to up to 3 years in jail.[35]

On 10 July,[7] which was 2 weeks after the police operations at GSK offices, Shanghai police arrested Humphrey and his wife Yu at their Shanghai apartment, charging them with privacy law breach. Harvard Humphrey, the son of Peter Humphrey accused of GSK of engaging his father “under false pretenses”, and described his father as "an honorable and law-abiding man". Humphrey and his wife Yu said that they accepted the offer as they believed that the bribery allegations were false and that they were investigating a smear campaign.[36] Humphrey said on Chinese national television that it was not his intention to break any Chinese law. He refused to confess to the charges levelled against him.[35][37]

Humphrey and Yu were found to have acquired 256 items of personal information. Humphrey was sentenced to 2 and a half and Yu was sentenced to 2 years by the Shanghai First Intermediate People’s Court, which was a much more severe sentence compared to other cases of similar conditions in Shanghai. After being denied care and tortured, Humphrey was released 7 months early and his wife Yu was released about the same time. They left China and went to the UK on 16 June 2015.[38]

Illegal dismissal[edit]

In the dismissal announced on 6 March 2015, 3 pregnant women and 4 nursing mothers were laid off. According to a former employee, the company talked to them individually, claiming that the employees had misbehavior and it had evidence for that. The company asked the employees to submit a resignation report by 9 March, and the company would consider it as a voluntary resignation. The employees were threatened by the company as it would leave a black mark in their employees' documents if the employees refused to comply with the requests. The laid-off employees' access to their office and emails were cut right on the day of the talk.[39]

GSK China identified and terminated more than 110 employees which it had "dismissed as a result of a crackdown on illegal expenses" during the period preceding the scandal.[40][41] The laid-off employees rallied before the GSK's Shanghai headquarter to protests against the dismissal.[39] Approximately half of the terminated workers appealed their dismissal, and GSK's refusal to reimburse employees for expenses incurred before termination, before a labour dispute arbitration committee.[40][41]

Vivian Shi and the whistleblower[edit]

According to the New York Times, the whistleblower could be more than one person, as the emails to regulators were written in fluent English via a Gmail account while the emails with a sex tape were written in poor English thorough a Chinese email service. One of the email addresses responded to the New York Times, which denied Vivian Shi as a whistleblower. The response added,[5]

I didn’t reveal to GSK personnel that I was the whistle-blower because doing so would have placed me in potential physical jeopardy. You understand that criminals — you know that they were convicted later in Chinese courts — were in charge of GSK China at that time, and I truly believe that they would have harmed me in some fashion had they discovered my identity.

The company denied that it was trying to dig out the whistleblower and instead the company was trying to fix a security hole for its employees.[42] In 2015, Shi rejoined the company that fired her three years ago. GSK confirmed the information but refused to make further comment. Friends of Humphrey/Yu couple believed Shi was a key figure in the couple's detention and the couple's investigations into Shi's political relations resulted in them being sent to jail.[43][44]

Investigations by other government[edit]

UK Serious Fraud Office[edit]

UK's Serious Fraud Office initiated an investigation in 2014, but the cased was closed by its new director Lisa Osofsky in 2019, after costing £7.5 million in the investigation. The Office's director said,[45][46][2]

"After an extensive and careful examination, I have concluded that there is either insufficient evidence to provide a realistic prospect of conviction or it is not in the public interest to bring a prosecution in these cases."

US Securities and Exchange Commission[edit]

As GSK bribery in China was a breach of US's Foreign Corrupt Practices Act during 2010–13, the Securities and Exchange Commission launched an investigation into the company. In September 2016, GSK agreed to pay a civil penalty of $20 million to settle the case, but it did not admit or deny the allegations.[47]

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