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Galactose-6-phosphate isomerase

From Wikipedia, the free encyclopedia
galactose-6-phosphate isomerase
Identifiers
EC no.5.3.1.26
CAS no.39433-98-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a galactose-6-phosphate isomerase (EC 5.3.1.26) is an enzyme that catalyzes the chemical reaction

D-galactose 6-phosphate D-tagatose 6-phosphate

Hence, this enzyme has one substrate, D-galactose 6-phosphate, and one product, D-tagatose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-galactose-6-phosphate aldose-ketose-isomerase. This enzyme participates in galactose metabolism.

References

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  • de Vos WM, Boerrigter I, van Rooyen RJ, Reiche B, Hengstenberg W (1990). "Characterization of the lactose-specific enzymes of the phosphotransferase system in Lactococcus lactis". J. Biol. Chem. 265 (36): 22554–60. PMID 2125052.
  • van Rooijen RJ, van Schalkwijk S, de Vos WM (1991). "Molecular cloning, characterization, and nucleotide sequence of the tagatose 6-phosphate pathway gene cluster of the lactose operon of Lactococcus lactis". J. Biol. Chem. 266 (11): 7176–81. PMID 1901863.