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Human leukocyte antigen serotype
HLA-B62 with bound peptide
major histocompatibility complex (human), class I, B62
Alleles
*1501, *1504, *1507, *1525
Structure (See HLA-B )
Shared data
Locus
chr.6 6p21.31
HLA-B62 (B62) is an HLA -B serotype . The serotype identifies certain B*15 gene-allele protein products of HLA-B.[ 1]
B62 is the largest of many split antigens of the broad antigen , B15 . B62 best identifies the B*1501, B*1504, B*1507 B*1525 and B*1533 allele products.
Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 [ 2]
B*15
B15
B62
B63
B70
B71
B72
B75
B76
B77
Sample
allele
%
%
%
%
%
%
%
%
%
size (N)
*1501
2
96
1906
*1504
10
69
29
*1505
18
64
22
*1506
40
20
11
10
*1507
79
101
*1508
20
18
45
*1511
15
27
21
68
*1512
17
18
8
12
*1515
13
49
28
138
*1520
100
5
*1524
44
54
*1525
7
74
8
116
*1527
7
76
76
*1528
14
57
14
7
*1530
17
64
98
*1531
50
12
*1535
79
34
Allele
B15
B62
B63
B70
B71
B72
B75
B76
B77
N
Alleles link-out to IMGT /HLA Databease at EBI
HLA B*1501 frequencies
freq
ref.
Population
(%)
[ 3] Japan Ainu Hokkaido
29.0
Chihuahuan Tarahumara
14.8
Autonomous Tibetans
12.3
South Korea ( 3)
10.5
Japan Central
8.7
Japan pop3
7.5
USA North American Natives
7.2
South Dakota Lakota Sioux
7.1
Shijiazhuang Tianjian Han
7.0
China Qinghai Hui
6.8
Croatia
6.7
Japan pop5
6.5
Portugal Centre
6.0
Taiwan Rukai
6.0
USA Alaska Yupik Natives
5.8
Australia New South Wales
5.6
USA European Americans (2)
5.6
France South East
5.5
China Beijing
5.3
Czech Republic
4.7
Ireland South
4.6
Mexico Sonora Seri
4.5
China Inner Mongolia
4.4
Russia Tuva (2)
4.2
Singapore Chinese
4.0
Taiwan Paiwan
3.9
China North Han
3.8
Georgia Svaneti Svans
3.8
Ireland Northern
3.8
Italy North Pavia
3.7
Mexico Mestizos
3.7
Azores Central Islands
3.6
Madeira
3.5
Taiwan Minnan pop 1
3.4
Azores Terceira Island
3.1
Taiwan Siraya
2.9
USA Hispanic
2.8
Taiwan Hakka
2.7
Taiwan Pazeh
2.7
China Yunnan Nu
2.6
Uganda Kampala
2.5
Argentina Toba Rosario
2.3
Romanian
2.3
Hong Kong Chinese
2.2
India North Hindus
1.9
New Caledonia
1.9
Italy South Campania
1.8
Taiwan Thao
1.7
India North Delhi
1.6
China Guangzhou
1.5
China Guangxi Maonan
1.4
China Yunnan Lisu
1.4
Thailand
1.4
PNG New Britain Rabaul
1.3
Brazil Belo Horizonte
1.1
Cameroon Yaounde
1.1
Portugal North
1.1
United Arab Emerates
1.1
Thailand pop3
1.0
USA African America
1.0
USA African Americans
1.0
Indig. Australian Yuendumu
0.8
PNG Wanigela
0.8
Mexico Zaptotec Oaxaca
0.7
Spain Eastern Andalusia
0.6
South African Natal Zulu
0.5
Spain E. Andalusia Gipsy
0.5
Sudanese
0.5
Taiwan Bunun
0.5
HLA B*1515 frequencies
freq
ref.
Population
(%)
[ 3] Mexico Mestizos
2.4
Mex. Guadalajara Mestizos (2)
1.9
Argentina Toba Rosario
1.2
China Guangdong Meizhou Han
1.0
China North Han
1.0
Cape Verde NW Islands
0.8
USA South Texas Hispanics
0.8
USA San Antonio Caucasians
0.6
USA Hispanic
0.4
USA Asian
0.3
USA North American Natives
0.3
USA African America
0.2
Hong Kong Chinese
0.1
HLA B*1525 frequencies
freq
ref.
Population
(%)
[ 3] Taiwan Tao
40.0
Taiwan Thao
11.7
Taiwan Pazeh
10.9
China Yunnan Lisu
8.7
China Yunnan Nu
8.3
PNG West Schrader Ranges
8.2
Indig. Australian Groote Eylandt
8.0
Taiwan Puyuma
7.0
Taiwan Rukai
7.0
Taiwan Bunun
6.4
Indig. Australian Yuendumu
5.7
Taiwan Siraya
4.9
Taiwan Tsou
4.9
Philippines Ivatan
3.0
Taiwan Atayal
2.8
Taiwan Ami
2.6
Thailand
2.5
China Guangzhou
2.0
Thailand pop3
2.0
Hong Kong Chinese
1.9
PNG Wanigela
1.5
PNG Wosera
1.5
Singapore Thai
1.5
India Andhra Pradesh Golla
1.4
PNG Eastern Highlands Goroka
1.4
China South Han
1.1
China Inner Mongolia
1.0
India North Hindus
1.0
HLA B*1507 frequencies
freq
ref.
Population
(%)
[ 3] Argentina Toba Rosario
8.1
New Mexico Canoncito Navajo
3.7
Brazil Terena
2.6
USA North American Natives
0.8
Japan Central
0.7
South Korea pop 3
0.6
Japan pop3
0.4
USA Asian
0.4
Shijiazhuang Tianjian Han
0.3
USA Caucasian pop2
0.2
Hong Kong Chinese
0.1
Ireland Northern
0.1
^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010" . Tissue Antigens . 75 (4): 291–455. doi :10.1111/j.1399-0039.2010.01466.x . PMC 2848993 PMID 20356336 . ^ derived from IMGT/HLA ^ a b c d Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database" . Tissue Antigens . 61 (5): 403–7. doi :10.1034/j.1399-0039.2003.00062.x PMID 12753660 .
