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Hexetidine

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Hexetidine
Clinical data
Pregnancy
category
  • Not to be used by pregnant women.
Routes of
administration
Topical (mouthwash)
ATC code
Identifiers
  • 1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.005.012 Edit this at Wikidata
Chemical and physical data
FormulaC21H45N3
Molar mass339.602 g/mol g·mol−1

Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1][2]

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for "the symptomatic treatment of 'strep' throat, tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery."

In the UK, Hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. This is produced by Pfizer. Oraldene mouthwash contains 0.1g/100ml of Hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40ml named "Hexoral" (by Pfizer) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash "Bactidol" (by Pfizer) which is sold in many Asian countries.

References

  1. ^ Kapić E, Becić F, Becić E (2002). "Hexetidine--an oral antiseptic". Med Arh. 56 (1): 43–8. PMID 11917691.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ "Oraldene". NetDoctor.co.uk. July 8, 2004. Retrieved 2007-04-03.
Hexetidine