Hydroxyglutamate decarboxylase

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hydroxyglutamate decarboxylase
Identifiers
EC number 4.1.1.16
CAS number 9024-59-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a hydroxyglutamate decarboxylase (EC 4.1.1.16) is an enzyme that catalyzes the chemical reaction

3-hydroxy-L-glutamate 4-amino-3-hydroxybutanoate + CO2

Hence, this enzyme has one substrate, 3-hydroxy-L-glutamate, and two products, 4-amino-3-hydroxybutanoate and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming). This enzyme is also called 3-hydroxy-L-glutamate 1-carboxy-lyase. It employs one cofactor, pyridoxal phosphate.

References[edit]

  • Umbreit WW, Heneage P (1953). "beta-Hydroxyglutamic acid decarboxylase". J. Biol. Chem. 201 (1): 15–20. PMID 13044771.