ITIH2

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ITIH2
Identifiers
Aliases ITIH2, H2P, SHAP, inter-alpha-trypsin inhibitor heavy chain 2
External IDs MGI: 96619 HomoloGene: 1668 GeneCards: ITIH2
RNA expression pattern
PBB GE ITIH2 204987 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002216

NM_010582

RefSeq (protein)

NP_002207

NP_034712.2
NP_034712

Location (UCSC) Chr 10: 7.7 – 7.75 Mb Chr 2: 10.09 – 10.13 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Inter-alpha-trypsin inhibitor heavy chain H2 is a protein that in humans is encoded by the ITIH2 gene.[3][4][5]

It is known to contain a Gla domain, and thus be dependent for production on post translational modification requiring vitamin K. Its function is also presumably dependent on calcium ions.

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Salier JP, Simon D, Rouet P, Raguenez G, Muscatelli F, Gebhard W, Guenet JL, Mattei MG (Dec 1992). "Homologous chromosomal locations of the four genes for inter-alpha-inhibitor and pre-alpha-inhibitor family in human and mouse: assignment of the ancestral gene for the lipocalin superfamily". Genomics. 14 (1): 83–8. doi:10.1016/S0888-7543(05)80287-3. PMID 1385302. 
  4. ^ Jean L, Risler JL, Nagase T, Coulouarn C, Nomura N, Salier JP (May 1999). "The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?". FEBS Lett. 446 (1): 6–8. doi:10.1016/S0014-5793(99)00173-8. PMID 10100603. 
  5. ^ "Entrez Gene: ITIH2 inter-alpha (globulin) inhibitor H2". 

Further reading[edit]