Lactate aldolase
| lactate aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.2.36 | ||||||||
| CAS no. | 110777-33-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a lactate aldolase (EC 4.1.2.36) is an enzyme that catalyzes the chemical reaction
- (S)-lactate formate + acetaldehyde
Hence, this enzyme has one substrate, (S)-lactate, and two products, formate and acetaldehyde.
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-lactate acetaldehyde-lyase (formate-forming). Other names in common use include lactate synthase, and (S)-lactate acetaldehyde-lyase. This enzyme participates in pyruvate metabolism.
References
- Gulyi MF, Silonova NV (1987). "[Various metabolic reactions of formate in animal tissues]". Ukr. Biokhim. Zh. 59 (4): 29–35. PMID 3629727.