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Lupanine 17-hydroxylase (cytochrome c)

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Lupanine 17-hydroxylase (cytochrome c)
Identifiers
EC no.1.17.2.2
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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Lupanine 17-hydroxylase (cytochrome c) (EC 1.17.2.2, lupanine dehydrogenase (cytochrome c)) is an enzyme with systematic name lupanine:cytochrome c-oxidoreductase (17-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

lupanine + 2 ferricytochrome c + H2O 17-hydroxylupanine + 2 ferrocytochrome c + 2 H+

The enzyme isolated from Pseudomonas putida contains heme c and requires pyrroloquinoline quinone (PQQ) for activity

References

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  1. ^ Hopper DJ, Rogozinski J, Toczko M (October 1991). "Lupanine hydroxylase, a quinocytochrome c from an alkaloid-degrading Pseudomonas sp". The Biochemical Journal. 279 ( Pt 1): 105–9. doi:10.1042/bj2790105. PMC 1151552. PMID 1656935.
  2. ^ Hopper DJ, Kaderbhai MA (April 2003). "The quinohaemoprotein lupanine hydroxylase from Pseudomonas putida". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1647 (1–2): 110–5. doi:10.1016/s1570-9639(03)00070-0. PMID 12686118.
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