Matheniko is a part of the corridor of protected areas in Karamoja that stretches from Kidepo National Park down through Bokora and Pian Upe Wildlife Reserves. The Reserve's northeastern boundary is also the Uganda-Kenya border.
^European Union. "Assessing protected areas in Africa". Global Environment Monitoring Unit of the Institute for Environment and Sustainability at the European Commission's Joint Research Centre. Retrieved 28 June 2012.