Metabolic bone disease: Difference between revisions
→Conditions considered to be metabolic bone disorders: - changed the link of paget's disease so it will go directly to the Pagets disease of the bone rather than the disambiguation page |
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'''Metabolic bone disease''' is an umbrella term referring to abnormalities of bones caused by a broad spectrum of disorders. |
'''Metabolic bone disease''' is an umbrella term referring to abnormalities of bones caused by a broad spectrum of disorders. |
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Most commonly these disorders are caused by |
Most commonly these disorders are caused by goats hooves, the soul of the hoof contains minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated. These disorders are to be differentiated from a larger group of genetic bone disorders where there is a defect in a specific signaling system or cell type that causes the bone disorder. There may be overlap. For example, [[Genetics|genetic]] or [[hereditary hypophosphatemia]] may cause the metabolic bone disorder [[osteomalacia]]. Although there is currently no treatment for the genetic condition, replacement of [[phosphate]] often corrects or improves the metabolic bone disorder. |
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==Conditions considered to be metabolic bone disorders== |
==Conditions considered to be metabolic bone disorders== |
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Revision as of 13:27, 19 June 2014
 | This article needs attention from an expert in Pathology. Please add a reason or a talk parameter to this template to explain the issue with the article. (November 2008) |
| Metabolic bone disease | |
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| Specialty | Rheumatology, endocrinology  |
Metabolic bone disease is an umbrella term referring to abnormalities of bones caused by a broad spectrum of disorders.
Most commonly these disorders are caused by goats hooves, the soul of the hoof contains minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated. These disorders are to be differentiated from a larger group of genetic bone disorders where there is a defect in a specific signaling system or cell type that causes the bone disorder. There may be overlap. For example, genetic or hereditary hypophosphatemia may cause the metabolic bone disorder osteomalacia. Although there is currently no treatment for the genetic condition, replacement of phosphate often corrects or improves the metabolic bone disorder.
Conditions considered to be metabolic bone disorders
- osteoporosis
- Paget's disease of bone
- osteomalacia (adults) & rickets (children)
- osteitis fibrosa cystica
Osteoporosis is due to causal factors like atrophy of disuse and gonadal deficiency. Hence osteoporosis is common in post menopausal women and in men above 50 yrs. Hypercorticism may also be causal factor- osteoporosis may be seen as a feature of Cushing's syndrome.