Methyl propionate

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Methyl propionate
Methyl propionate.svg
Preferred IUPAC name
Methyl propanoate
Other names
Methyl propionate
Propanoic acid, methyl ester
Propionic acid, methyl ester
3D model (JSmol)
ECHA InfoCard 100.008.238
Molar mass 88.11 g·mol−1
Appearance Colorless liquid[1]
Density 0.915 g/mL[1]
Melting point −88 °C (−126 °F; 185 K)[1]
Boiling point 80 °C (176 °F; 353 K)[1]
72 g/L (20 °C)[1]
-55.0·10−6 cm3/mol
Flash point −2 °C (28 °F; 271 K)[1]
465 °C (869 °F; 738 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Methyl propionate, also known as methyl propanoate, is a chemical compound with the molecular formula C4H8O2. It is a clear liquid with a fruity, rum-like odor.[2]


Methyl propanoate can be prepared by esterification of propionic acid with methanol. Industrially, it is prepared by carboalkoxylation, i.e., the reaction of ethylene with carbon monoxide and methanol in the presence of a catalyst:

C2H4 + CO + MeOH → MeO2CCH2CH3

The reaction is catalyzed by nickel carbonyl and palladium(0) complexes.[3][4]


Condensation of Methyl propionate with formaldehyde followed by dehydration yields methyl methacrylate:[4]


Methyl propionate is used as a solvent for cellulose nitrate and lacquers, and as a raw material for the production of paints, varnishes and other chemicals such as methyl methacrylate.[2][3]

Due to its fruity smell and taste, it is also used in fragrances and flavoring.[2][5]


  1. ^ a b c d e f g Record in the GESTIS Substance Database of the Institute for Occupational Safety and Health
  2. ^ a b c "Methyl Propionate Hazardous Substance Fact Sheet" (PDF). New Jersey Department of Health and Senior Services.
  3. ^ a b Ulf-Rainer Samel; Walter Kohler; Armin Otto Gamer; Ullrich Keuser (2000). Propionic Acid and Derivatives. Ullmann's Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a22_223.pub2. ISBN 9783527306732.(mayth and yafs)
  4. ^ a b Scott D. Barnicki "Synthetic Organic Chemicals" in Handbook of Industrial Chemistry and Biotechnology edited by James A. Kent, New York : Springer, 2012. 12th ed. ISBN 978-1-4614-4259-2.
  5. ^ "Methyl propionate".