Jump to content

Mycinamicin VI 2''-O-methyltransferase

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Dcirovic (talk | contribs) at 01:59, 22 May 2016 (top: clean up using AWB). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Mycinamicin VI 2-O-methyltransferase
Identifiers
EC no.2.1.1.238
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Mycinamicin VI 2-O-methyltransferase (EC 2.1.1.238, MycE) is an enzyme with systematic name S-adenosyl-L-methionine:mycinamicin VI 2-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + mycinamicin VI S-adenosyl-L-homocysteine + mycinamicin III

The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.

References

  1. ^ Li, S.; Anzai, Y.; Kinoshita, K.; Kato, F.; Sherman, D.H. (2009). "Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics". Chembiochem. 10 (8): 1297–1301. doi:10.1002/cbic.200900088. PMID 19415708.