NANS

NANS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WVO
Identifiers
Aliases	NANS, HEL-S-100, SAS, N-acetylneuraminate synthase, SEMDG, SEMDCG
External IDs	OMIM: 605202; MGI: 2149820; HomoloGene: 10343; GeneCards: NANS; OMA:NANS - orthologs
EC number	2.5.1.57
Gene location (Human)
Chr.	Chromosome 9 (human)
End	98,083,077 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,503,632 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; mucosa of transverse colon; ; rectum; ; epithelium of nasopharynx; ; olfactory zone of nasal mucosa; ; palpebral conjunctiva; ; parotid gland; ; prostate; ; trachea; ; bronchial epithelial cell;
	Top expressed in
	left colon; ; submandibular gland; ; lacrimal gland; ; seminal vesicula; ; basilar part of occipital bone; ; parotid gland; ; crypt of lieberkuhn of small intestine; ; prostate; ; endothelial cell of lymphatic vessel; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	N-acetylneuraminate synthase activity; transferase activity; catalytic activity; N-acylneuraminate cytidylyltransferase activity; N-acylneuraminate-9-phosphate synthase activity;
Cellular component	cytoplasm; cytosol; extracellular exosome;
Biological process	carbohydrate biosynthetic process; CMP-N-acetylneuraminate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	54187
	94181
	ENSG00000095380
	ENSMUSG00000028334
	Q9NR45; Q5TBR0
	Q99J77
	NM_018946
	NM_053179
	NP_061819
	NP_444409
	Wikidata
View/Edit Human	View/Edit Mouse

Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000095380 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028334 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lawrence SM, Huddleston KA, Pitts LR, Nguyen N, Lee YC, Vann WF, Coleman TA, Betenbaugh MJ (Jul 2000). "Cloning and expression of the human N-acetylneuraminic acid phosphate synthase gene with 2-keto-3-deoxy-D-glycero- D-galacto-nononic acid biosynthetic ability". J Biol Chem. 275 (23): 17869–77. doi:10.1074/jbc.M000217200. PMID 10749855.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

References

Further reading