Jump to content

Fluoroethyl-L-tyrosine (18F)

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by DePiep (talk | contribs) at 20:52, 5 April 2016 (Remove redundant parameters InChI, InChIKey (StdInChI, StdInChIKey are used). See Talk (via AWB script)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

O-(2-Fluorethyl)-L-thyrosine
Clinical data
Other names18F-FET; O-(2-(18F)fluoroethyl)-L-tyrosine, O-(2-fluoroethyl)tyrosine, L-(18F)FET[1]
Routes of
administration
intravenous
Identifiers
  • (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H14FNO3
Molar mass227.23 g/mol g·mol−1
3D model (JSmol)
  • C1=CC(=CC=C1CC(C(=O)O)N)OCCF
  • InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1
  • Key:QZZYPHBVOQMBAT-JTQLQIEISA-N

O-(2-Fluorethyl)-L-thyrosine or 18F-FET is an neuro-oncologic PET tracer.[2]

References

  1. ^ CID 54255856 from PubChem
  2. ^ Galldiks, N.; Stoffels, G.; Filss, C.; Rapp, M.; Blau, T.; Tscherpel, C.; Ceccon, G.; Dunkl, V.; Weinzierl, M.; Stoffel, M.; Sabel, M.; Fink, G. R.; Shah, N. J.; Langen, K.-J. (2015). "The use of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma". Neuro-Oncology. doi:10.1093/neuonc/nov088.