PCDH10

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PCDH10
Identifiers
AliasesPCDH10, OL-PCDH, PCDH19, protocadherin 10
External IDsMGI: 1338042 HomoloGene: 74967 GeneCards: PCDH10
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for PCDH10
Genomic location for PCDH10
Band4q28.3Start133,149,315 bp[1]
End133,208,606 bp[1]
RNA expression pattern
PBB GE PCDH10 gnf1h00367 s at fs.png

PBB GE PCDH10 gnf1h01052 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020815
NM_032961

NM_001098170
NM_001098171
NM_001098172
NM_011043

RefSeq (protein)

NP_065866
NP_116586

n/a

Location (UCSC)Chr 4: 133.15 – 133.21 MbChr 3: 45.38 – 45.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.[5][6]

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138650 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049100 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Nollet F, Kools P, van Roy F (Jul 2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members". J Mol Biol. 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267.
  6. ^ a b "Entrez Gene: PCDH10 protocadherin 10".

Further reading[edit]