PEX13

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PEX13
Protein PEX13 PDB 1wxu.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PEX13, NALD, PBD11A, PBD11B, ZWS, peroxisomal biogenesis factor 13
External IDs MGI: 1919379 HomoloGene: 1967 GeneCards: PEX13
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for PEX13
Genomic location for PEX13
Band 2p15 Start 61,017,225 bp[1]
End 61,051,990 bp[1]
RNA expression pattern
PBB GE PEX13 205246 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002618

NM_023651

RefSeq (protein)

NP_002609

NP_076140

Location (UCSC) Chr 2: 61.02 – 61.05 Mb Chr 11: 23.65 – 23.67 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Peroxisomal membrane protein PEX13 is a protein that in humans is encoded by the PEX13 gene.[5][6] It located on chromosome 2 next to KIAA1841

Interactions[edit]

PEX13 has been shown to interact with PEX14,[7] PEX5[7][8] and PEX19.[9][10]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162928 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020283 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Bjorkman J, Stetten G, Moore CS, Gould SJ, Crane DI (February 1999). "Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene". Genomics. 54 (3): 521–8. doi:10.1006/geno.1998.5520. PMID 9878256. 
  6. ^ "Entrez Gene: PEX13 peroxisome biogenesis factor 13". 
  7. ^ a b Otera, Hidenori; Setoguchi Kiyoko; Hamasaki Maho; Kumashiro Toshitaka; Shimizu Nobuhiro; Fujiki Yukio (March 2002). "Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import". Mol. Cell. Biol. United States. 22 (6): 1639–55. doi:10.1128/MCB.22.6.1639-1655.2002. ISSN 0270-7306. PMC 135613Freely accessible. PMID 11865044. 
  8. ^ Gould, S J; Kalish J E; Morrell J C; Bjorkman J; Urquhart A J; Crane D I (October 1996). "Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor". J. Cell Biol. UNITED STATES. 135 (1): 85–95. doi:10.1083/jcb.135.1.85. ISSN 0021-9525. PMC 2121023Freely accessible. PMID 8858165. 
  9. ^ Sacksteder, K A; Jones J M; South S T; Li X; Liu Y; Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. UNITED STATES. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547Freely accessible. PMID 10704444. 
  10. ^ Fransen, M; Wylin T; Brees C; Mannaerts G P; Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. United States. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101Freely accessible. PMID 11390669. 

Further reading[edit]

External links[edit]