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Peroxisomal biogenesis factor 13
Protein PEX13 PDB 1wxu.png
PDB rendering based on 1wxu.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols PEX13 ; NALD; PBD11A; PBD11B; ZWS
External IDs OMIM601789 MGI1919379 HomoloGene1967 GeneCards: PEX13 Gene
RNA expression pattern
PBB GE PEX13 205246 at tn.png
More reference expression data
Species Human Mouse
Entrez 5194 72129
Ensembl ENSG00000162928 ENSMUSG00000020283
UniProt Q92968 Q9D0K1
RefSeq (mRNA) NM_002618 NM_023651
RefSeq (protein) NP_002609 NP_076140
Location (UCSC) Chr 2:
61.02 – 61.05 Mb
Chr 11:
23.65 – 23.67 Mb
PubMed search [1] [2]

Peroxisomal membrane protein PEX13 is a protein that in humans is encoded by the PEX13 gene.[1][2] It located on chromosome 2 next to KIAA1841


PEX13 has been shown to interact with PEX14,[3] PEX5[3][4] and PEX19.[5][6]


  1. ^ Bjorkman J, Stetten G, Moore CS, Gould SJ, Crane DI (February 1999). "Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene". Genomics 54 (3): 521–8. doi:10.1006/geno.1998.5520. PMID 9878256. 
  2. ^ "Entrez Gene: PEX13 peroxisome biogenesis factor 13". 
  3. ^ a b Otera, Hidenori; Setoguchi Kiyoko; Hamasaki Maho; Kumashiro Toshitaka; Shimizu Nobuhiro; Fujiki Yukio (March 2002). "Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import". Mol. Cell. Biol. (United States) 22 (6): 1639–55. doi:10.1128/MCB.22.6.1639-1655.2002. ISSN 0270-7306. PMC 135613. PMID 11865044. 
  4. ^ Gould, S J; Kalish J E; Morrell J C; Bjorkman J; Urquhart A J; Crane D I (October 1996). "Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor". J. Cell Biol. (UNITED STATES) 135 (1): 85–95. doi:10.1083/jcb.135.1.85. ISSN 0021-9525. PMC 2121023. PMID 8858165. 
  5. ^ Sacksteder, K A; Jones J M; South S T; Li X; Liu Y; Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. (UNITED STATES) 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547. PMID 10704444. 
  6. ^ Fransen, M; Wylin T; Brees C; Mannaerts G P; Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. (United States) 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101. PMID 11390669. 

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