PPRC1

PPRC1
Identifiers
Aliases	PPRC1, PRC, peroxisome proliferator-activated receptor gamma, coactivator-related 1, PPARG related coactivator 1
External IDs	OMIM: 617462; MGI: 2385096; HomoloGene: 9006; GeneCards: PPRC1; OMA:PPRC1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	102,150,333 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	46,061,354 bp
RNA expression pattern
	Top expressed in
	left uterine tube; ; oocyte; ; skin of abdomen; ; upper lobe of left lung; ; anterior pituitary; ; secondary oocyte; ; body of pancreas; ; gastric mucosa; ; body of stomach; ; tibial nerve;
	Top expressed in
	otic placode; ; saccule; ; primitive streak; ; morula; ; hair follicle; ; yolk sac; ; abdominal wall; ; condyle; ; molar; ; lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nuclear receptor coactivator activity; nucleic acid binding; transcription coregulator activity; RNA binding; transcription factor binding;
Cellular component	nucleus; nucleoplasm;
Biological process	positive regulation of DNA-binding transcription factor activity; mitochondrion organization; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	23082
	226169
	ENSG00000148840
	ENSMUSG00000055491
	Q5VV67
	Q6NZN1
	NM_001288727; NM_001288728; NM_015062
	NM_001081214; NM_145504; NM_001346801
	NP_001275656; NP_001275657; NP_055877
	NP_001074683; NP_001333730
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

PPRC1 has been shown to interact with USF2.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000148840 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055491 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
^ Andersson U, Scarpulla RC (May 2001). "PGC-1-Related Coactivator, a Novel, Serum-Inducible Coactivator of Nuclear Respiratory Factor 1-Dependent Transcription in Mammalian Cells". Mol Cell Biol. 21 (11): 3738–49. doi:10.1128/MCB.21.11.3738-3749.2001. PMC 87014. PMID 11340167.
^ "Entrez Gene: PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1".
^ Moore, Meredith L; Park Edwards A; McMillin Jeanie B (May 2003). "Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1". J. Biol. Chem. 278 (19). United States: 17263–8. doi:10.1074/jbc.M210486200. ISSN 0021-9258. PMID 12611894. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading