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PRPSAP2

From Wikipedia, the free encyclopedia
PRPSAP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRPSAP2, PAP41, phosphoribosyl pyrophosphate synthetase associated protein 2
External IDsOMIM: 603762; MGI: 2384838; HomoloGene: 2073; GeneCards: PRPSAP2; OMA:PRPSAP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 17: 18.84 – 18.93 MbChr 11: 61.62 – 61.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphoribosyl pyrophosphate synthetase-associated protein 2 is a protein that in humans is encoded by the PRPSAP2 gene.[5]

Function

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The enzyme phosphoribosyl pyrophosphate synthetase (PRS) catalyzes the formation of phosphoribosyl pyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141127Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020528Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: phosphoribosyl pyrophosphate synthetase-associated protein 2". Retrieved 2011-08-30.

Further reading

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