The Pelatiah Leete House is a historic house at 575 Leete's Island Road in Guilford, Connecticut, United States. It is a 2-1/2 story wood frame structure, five bays wide, with a large central chimney and a center entrance. The rear of the house has an extended leanto section, giving the house a classic New England colonial saltbox appearance. The house was built in 1710 by Pelatiah Leete, the grandson of William Leete, a governor of the New Haven Colony. It is the oldest surviving house of several in the area belong to members of the Leete family.