RGS5

RGS5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CRP
Identifiers
Aliases	RGS5, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129, regulator of G-protein signaling 5, regulator of G protein signaling 5
External IDs	OMIM: 603276; MGI: 1098434; HomoloGene: 2682; GeneCards: RGS5; OMA:RGS5 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	163,321,791 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	169,523,382 bp
RNA expression pattern
	Top expressed in
	Descending thoracic aorta; ; cardia; ; urethra; ; pylorus; ; popliteal artery; ; tibial arteries; ; ascending aorta; ; visceral pleura; ; seminal vesicula; ; right ventricle;
	Top expressed in
	tunica media of zone of aorta; ; transitional epithelium of urinary bladder; ; body of femur; ; ankle; ; olfactory epithelium; ; digastric muscle; ; sternocleidomastoid muscle; ; temporal muscle; ; triceps brachii muscle; ; medial head of gastrocnemius muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	GTPase activator activity; GTPase activity;
Cellular component	plasma membrane; membrane; cytoplasm; cytosol;
Biological process	negative regulation of signal transduction; regulation of G protein-coupled receptor signaling pathway; positive regulation of GTPase activity; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	8490
	19737
	ENSG00000143248
	ENSMUSG00000026678
	O15539
	O08850
	NM_001195303; NM_001254748; NM_001254749; NM_003617; NM_025226
	NM_009063; NM_001313705
	NP_001182232; NP_001241677; NP_001241678; NP_003608; NP_003608.1
	NP_001300634; NP_033089
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.^[5]^[6]

Template:PBB Summary

Interactions

RGS5 has been shown to interact with GNAO1,^[7]^[8] GNAI2^[7]^[8] and GNAI3.^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143248 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026678 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seki N, Sugano S, Suzuki Y, Nakagawara A, Ohira M, Muramatsu M, Saito T, Hori T (October 1998). "Isolation, tissue expression, and chromosomal assignment of human RGS5, a novel G-protein signaling regulator gene". J Hum Genet. 43 (3): 202–5. doi:10.1007/s100380050071. PMID 9747037.
^ "Entrez Gene: RGS5 regulator of G-protein signalling 5".
^ ^a ^b ^c Chen, C; Zheng B; Han J; Lin S C (March 1997). "Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast". J. Biol. Chem. 272 (13). UNITED STATES: 8679–85. doi:10.1074/jbc.272.13.8679. ISSN 0021-9258. PMID 9079700. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)
^ ^a ^b ^c Zhou, J; Moroi K; Nishiyama M; Usui H; Seki N; Ishida J; Fukamizu A; Kimura S (February 2001). "Characterization of RGS5 in regulation of G protein-coupled receptor signaling". Life Sci. 68 (13). England: 1457–69. doi:10.1016/S0024-3205(01)00939-0. ISSN 0024-3205. PMID 11253162. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading