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Rho-related BTB domain containing 1
Symbols RHOBTB1 ; KIAA0740; MGC33059; MGC33841
External IDs OMIM607351 MGI1916538 HomoloGene8892 GeneCards: RHOBTB1 Gene
RNA expression pattern
PBB GE RHOBTB1 212651 at tn.png
More reference expression data
Species Human Mouse
Entrez 9886 69288
Ensembl ENSG00000072422 ENSMUSG00000019944
UniProt O94844 Q9DAK3
RefSeq (mRNA) NM_001242359 NM_001081347
RefSeq (protein) NP_001229288 NP_001074816
Location (UCSC) Chr 10:
60.87 – 61 Mb
Chr 10:
69.15 – 69.29 Mb
PubMed search [1] [2]

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene.[1][2]

The protein encoded by this gene belongs to the Rho family of the Ras superfamily of small GTPases. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.[2]


  1. ^ Rivero F, Dislich H, Glockner G, Noegel AA (Mar 2001). "The Dictyostelium discoideum family of Rho-related proteins". Nucleic Acids Res 29 (5): 1068–79. doi:10.1093/nar/29.5.1068. PMC 29714. PMID 11222756. 
  2. ^ a b "Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1". 

Further reading[edit]