Region IV of hippocampus proper

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Region IV of hippocampus proper
Diagram of hippocampal regions in a rat brain.
CajalHippocampus (modified).png
Basic circuit of the hippocampus, shown using a modified drawing by Ramon y Cajal. DG: dentate gyrus. Sub: subiculum. EC: entorhinal cortex
Latin regio hippocampi proprii IV; regio IV cornus ammonis; CA4
TA A14.1.09.331
FMA 75741
Anatomical terms of neuroanatomy

Region IV of hippocampus proper is a portion of the hippocampal formation.

Region CA4 (often called the hilus or hilar region when considered part of the dentate gyrus, as neurons here do not have pyramidal morphology like those of areas CA1 & CA3 (suggested by Lorente de Nó[1] and verified by David G. Amaral))[2] contains mossy cells that primarily receive inputs from granule cells located nearby in the dentate gyrus in the form of mossy fibers. They also receive a small number of connections from pyramidal cells located in CA3. They, in turn, project back into the dentate gyrus at distant septotemporal levels.

Additional images[edit]


  1. ^ Lorente de Nó, R (1934). "Studies on the structure of the cerebral cortex. Continuation of the study of the ammonic system". J. Psychol. Neurol. 46: 113–177. 
  2. ^ Amaral, DG (1978). "A Golgi study of cell types in the hilar region of the hippocampus in the rat". J. Comp. Neurol. 15 (5): 851–914. doi:10.1002/cne.901820508. PMID 730852.