SH3BP2

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SH3-domain binding protein 2
Identifiers
Symbol SH3BP2
Entrez 6452
HUGO 10825
OMIM 602104
RefSeq NM_003023
UniProt P78314
Other data
Locus Chr. 4 p16.3

SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. It binds to phosphatidylinositols linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. It is also associated with cherubism.

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