SKIL

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SKIL
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SKIL, SNO, SnoA, SnoI, SnoN, SKI-like proto-oncogene
External IDs MGI: 106203 HomoloGene: 3948 GeneCards: SKIL
RNA expression pattern
PBB GE SKIL 206675 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145097
NM_001145098
NM_001248008
NM_005414

NM_001039090
NM_001271772
NM_011386

RefSeq (protein)

NP_001138569
NP_001138570
NP_001234937
NP_005405

NP_001034179.1
NP_035516.2
NP_001034179
NP_001258701
NP_035516

Location (UCSC) Chr 3: 170.36 – 170.4 Mb Chr 3: 31.1 – 31.12 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ski-like protein is a protein that in humans is encoded by the SKIL gene.[3][4]


Interactions[edit]

SKIL has been shown to interact with SKI protein,[5] Mothers against decapentaplegic homolog 3[6][7] and Mothers against decapentaplegic homolog 2.[6][7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Nomura N; Sasamoto S; Ishii S; Date T; Matsui M; Ishizaki R (September 1989). "Isolation of human cDNA clones of ski and the ski-related gene, sno". Nucleic Acids Res. 17 (14): 5489–500. doi:10.1093/nar/17.14.5489. PMC 318172Freely accessible. PMID 2762147. 
  4. ^ "Entrez Gene: SKIL SKI-like oncogene". 
  5. ^ Cohen, S B; Zheng G; Heyman H C; Stavnezer E (February 1999). "Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents". Nucleic Acids Res. ENGLAND. 27 (4): 1006–14. doi:10.1093/nar/27.4.1006. ISSN 0305-1048. PMC 148280Freely accessible. PMID 9927733. 
  6. ^ a b Stroschein, S L; Bonni S; Wrana J L; Luo K (November 2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev. United States. 15 (21): 2822–36. doi:10.1101/gad.912901. ISSN 0890-9369. PMC 312804Freely accessible. PMID 11691834. 
  7. ^ a b Stroschein, S L; Wang W; Zhou S; Zhou Q; Luo K (October 1999). "Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein". Science. UNITED STATES. 286 (5440): 771–4. doi:10.1126/science.286.5440.771. ISSN 0036-8075. PMID 10531062. 

Further reading[edit]