Raphanin
(Redirected from Sulforaphen)
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| Names | |
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| Preferred IUPAC name
(1E)-4-Isothiocyanato-1-(methanesulfinyl)but-1-ene | |
| Other names
Sulforaphen; Sulforaphene; Sativin
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C6H9NOS2 | |
| Molar mass | 175.26 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage.[1][2] It was first described in 1947.[3][4]
Basic research
[edit]In vitro, raphanin inhibits some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli.[3][5][6]
| Bacteria | MIC (mg/mL) |
|---|---|
| Staphylococcus | 0.04 |
| Shigella dysenteriae | 0.125 |
| Salmonella typhi | 0.125 |
| Escherichia coli | 0.2 |
See also
[edit]References
[edit]- ^ Sinha, Nirmal K.; Hui, Y. H.; Muhammad Siddiq; Jasim Ahmed (2010). Handbook of Vegetables and Vegetable Processing. John Wiley and Sons. p. 156. ISBN 978-0-8138-1541-1.
- ^ Michael Meyer & Sieghard T. Adam (2008). "Comparison of glucosinolate levels in commercial broccoli and red cabbage from conventional and ecological farming". European Food Research and Technology. 226 (6): 1429–1437. doi:10.1007/s00217-007-0674-0. S2CID 98687281.
- ^ a b Baron, Abraham Louis (1950). Handbook of antibiotics. Reinhold. p. 215. ISBN 9780598986818.
- ^ Ivãnovics, G. & S. Horvãth (1947). "Raphanin, an Antibacterial Principle of the Radish (Raphanus sativus)". Nature. 160 (4061): 297–298. Bibcode:1947Natur.160..297I. doi:10.1038/160297a0. PMID 20261763. S2CID 4005718.
- ^ Florey, Howard (1949). Antibiotics: a survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. Oxford University Press. pp. 625–6.
- ^ Ivànovics, G. & Horvath, S. (1947). "Isolation and Properties of Raphanin, an Antibacterial Substance from Radish Seed". Experimental Biology and Medicine. 66 (3): 625–630. doi:10.3181/00379727-66-16177. PMID 18900045. S2CID 32292410.
- ^ Chang, Hson-Mou; Pui-Hay, Paul; Yao, Sih-Cheng (2001). Pharmacology and Applications of Chinese Material Medical. World Scientific. p. 969. ISBN 978-981-02-3694-6.